L-Thyroxine (T4) solution, 100 mug/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material

Code: T-073-1ML D2-231

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicul...


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€92.80 1ML
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Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.

General description

Thyroxine or T4 is a thyroid hormone responsible for regulation of the body′s basal metabolic rate and essential for growth, development and heart and nervous system function. Free and total T4 serum levels are measured by LC-MS/MS for determination of hyper- or hypothyroidism as well as for monitoring treatment with synthetic thyroid hormones. This Certified Spiking Solution® is suitable for use in LC-MS/MS testing methods as starting materials in preparation of linearity standards, calibrators, and controls.

Legal Information

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

CERTIFIED SPIKING SOLUTIONS is a registered trademark of Cerilliant Corporation

CERILLIANT is a registered trademark of Cerilliant Corporation

application(s)clinical testingclinical testing
concentration100 µg/mL in methanol with 0.1N NH3
featureSnap-N-Spike®/Snap-N-Shoot®
formliquid
formatsingle component solution
Gene Informationhuman ... THRA(7067), THRB(7068)
gradecertified reference material
InChI keyXUIIKFGFIJCVMT-LBPRGKRZSA-N
InChI1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
manufacturer/tradenameCerilliant®
mp223 °C (dec.) (lit.)
packagingampule of 1 mL
Quality Level300
SMILES stringN[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
storage temp.−20°C
technique(s)gas chromatography (GC): suitable, liquid chromatography (LC): suitable
Cas Number51-48-9
Hazard Class3
Un Number1230
Pack GroupII
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